Women Who Rock: No 2. Karen O of Yeah Yeah Yeahs
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2. Karen O.
Why She Rocks: From orgasmic screeches to epileptic body-thrashing, Karen O is more than an idiosyncratic rocker with an unnatural affinity for spandex. The Yeah Yeah Yeahs' frontwoman is a self-possessed force of nature who'll dizzy you up with lyrical riddles, douse you in beer and then sing you a love song to rest your pretty little head.
Most Rockin' Moment: After cursing a blue streak during the band's homecoming gigs in February, Karen O looked up to the balcony at New York's Bowery Ballroom and dedicated 'Maps' to a special birthday girl: Her mom.
Listen to Karen's stripped-down show in our studio

Han Myung-Gu / WireImage.com